PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs6191 dbSNP Ensembl
Location	5:143278591 - 143278591(+)
Variant Seq	A
Ancestral Allele	A
Ref Seq	C
Minor Allele Frequence	0.401558
Annotation	downstream_gene_variant; 3_prime_UTR_variant
Variant Effect	downstream_gene_variant(ENST00000424646, ENST00000504572, ENST00000394466, ENST00000231509, ENST00000503201); 3_prime_UTR_variant(ENST00000415690, ENST00000394464, ENST00000343796)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000378004, ENST00000418236, ENST00000443674, ENST00000274498)
PolyPhen Annotation	benign; possibly_damaging
PolyPhen Variant Effect	benign(ENST00000378004, ENST00000418236); possibly_damaging(ENST00000443674, ENST00000274498)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription;Enhancers;Strong transcription;Genic enhancers
No. of Marker's Association Results	0 (Positive: 0; Negative: 0; Trend: 0)
Source	LD-proxy

SNP related association results

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
NR3C1	nuclear receptor subfamily 3 group C member 1	5q31-q32	6(2/4/0)

SNPs in LD with rs6191 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1-IT1	Yes	Adipose Subcutaneous	cis	GTEx