SNP Report

Basic Info

Name	rs265983 dbSNP Ensembl
Location	5:175408114 - 175408114(+)
Variant Seq	T
Ancestral Allele	T
Ref Seq	A
Minor Allele Frequence	0.302516
Annotation	downstream_gene_variant
SIFT Annotation	deleterious; tolerated
SIFT Variant Effect	deleterious(ENST00000507785); tolerated(ENST00000239243)
PolyPhen Annotation	benign; probably_damaging
PolyPhen Variant Effect	benign(ENST00000239243); probably_damaging(ENST00000507785)
rSNP?	No Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Inactive region
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Nelson, E. C.,2014	PTSD	P-value=0.015, OR=0.82 P-value=0.015, OR=0.82	Although the association of this SNP is of considerably lowe...... Although the association of this SNP is of considerably lower magnitude, it is interesting to note. More...	Non-significant

SNP related genes (count: 0)

SNPs in LD with rs265983 (count: 3)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs2080832	rs265983	downstream_gene_variant	0.8274[EUR]
rs265982	rs265983	downstream_gene_variant	1.0000[EUR]
rs2644631	rs265983	downstream_gene_variant	0.8937[EUR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1-IT1	Yes	Adipose Subcutaneous	cis	GTEx