SNP Report
Basic Info
| Name | rs263234 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 8:130806469 - 130806469(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | A | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.201877 | ||
| Annotation | intron_variant | ||
| Variant Effect | intron_variant(ENST00000286355, ENST00000377928) | ||
| SIFT Annotation | deleterious; tolerated | ||
| SIFT Variant Effect | deleterious(ENST00000286355); tolerated(ENST00000377928) | ||
| PolyPhen Annotation | benign; probably_damaging | ||
| PolyPhen Variant Effect | benign(ENST00000377928); probably_damaging(ENST00000286355) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription;Enhancers | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Wolf, E. J.,2014 | Dissociative symptom severity | P-value<0.05 P-value<0.05 | Follow-up evaluation of ADCY8 revealed four other SNPs (rs43...... Follow-up evaluation of ADCY8 revealed four other SNPs (rs4339660, rs7015079, rs263238, and rs263234) that were nominally associated with dissociation severity (smallest P-value= .01). More... | Non-significant |
SNP related genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| ZNF276 | zinc finger protein 276 | 16q24.3 | rSNP target |
| ADCY8 | adenylate cyclase 8 (brain) | 8q24 | 1(0/0/1) |
| VPS9D1 | VPS9 domain containing 1 | 16q24.3 | rSNP target |
SNPs in LD with rs263234 (count: 9)
Literature-origin SNPs (count: 0)
LD-proxies (count: 9)
SNP related eQTL (count: 1)