PTSDgene database

SNP Report

Basic Info
Name rs2041568 dbSNP Ensembl
Location 7:31101804 - 31101804(+)
Variant Seq C
Ancestral Allele C
Ref Seq T
Minor Allele Frequence 0.261182
Annotation intron_variant
Variant Effect intron_variant(ENST00000409489, ENST00000396211, ENST00000614107, ENST00000436116, ENST00000304166, ENST00000409363)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000614107, ENST00000304166, ENST00000409363, ENST00000409489, ENST00000396211)
PolyPhen Annotation benign; probably_damaging; possibly_damaging
PolyPhen Variant Effect benign(ENST00000614107, ENST00000396211); probably_damaging(ENST00000409363); possibly_damaging(ENST00000304166, ENST00000409489)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers;Strong transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ressler, K. J.,2011 PTSD diagnosis Females: P-value=0.149, males: P-value=0.611 Females: P-value=0.149, males: P-value=0.611 No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs2041568 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx