SNP Report
Basic Info
| Name | rs1915919 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 3:20042389 - 20042389(+) | ||
| Variant Seq | T | ||
| Ancestral Allele | T | ||
| Ref Seq | C | ||
| Minor Allele Frequence | 0.276757 | ||
| Annotation | intron_variant; non_coding_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000263754, ENST00000426228); non_coding_transcript_variant(ENST00000426228) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000263754) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000263754) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription;Enhancers;Genic enhancers;Flanking Active TSS;Active TSS | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 0; Trend: 1) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Wolf, E. J.,2014 | Dissociative symptom severity |
Linear regression: B=0.74, SE=0.16, P-value=7.99E-06, R |
It showed suggestive evidence of association with dissociati...... It showed suggestive evidence of association with dissociation. In follow-up analyses, the association between this SNP and dissociation severity remained significant after covarying for PTSD severity. More... | Trend |
SNP related genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| EFHB | EF-hand domain family member B | 3p24.3 | rSNP target |
| KAT2B | K(lysine) acetyltransferase 2B | 3p24 | 1(0/0/1) |
| RAB5A | RAB5A, member RAS oncogene family | 3p24.3 | rSNP target |
SNPs in LD with rs1915919 (count: 1)
Literature-origin SNPs (count: 0)
LD-proxies (count: 1)
SNP related eQTL (count: 1)