PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs1541516 dbSNP Ensembl
Location	7:31082927 - 31082927(+)
Variant Seq	A
Ancestral Allele	G
Ref Seq	G
Minor Allele Frequence	0.271166
Annotation	downstream_gene_variant; upstream_gene_variant; intron_variant
Variant Effect	downstream_gene_variant(ENST00000431811); upstream_gene_variant(ENST00000436116); intron_variant(ENST00000409363, ENST00000304166, ENST00000409489, ENST00000396211, ENST00000614107)
SIFT Annotation	deleterious; tolerated
SIFT Variant Effect	deleterious(ENST00000409489, ENST00000614107, ENST00000396211); tolerated(ENST00000304166, ENST00000409363)
PolyPhen Annotation	possibly_damaging; probably_damaging
PolyPhen Variant Effect	possibly_damaging(ENST00000614107, ENST00000396211); probably_damaging(ENST00000409489, ENST00000304166, ENST00000409363)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	TF binding region;Chromatin interactive region
Chromatin State	Weak transcription;Enhancers;Strong transcription;Bivalent Enhancer;Genic enhancers;Bivalent/Poised TSS
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Ressler, K. J.,2011	PTSD diagnosis	Females: P-value=0.858, males: P-value=0.941 Females: P-value=0.858, males: P-value=0.941	No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	7p14.3	19(8/11/0)

SNPs in LD with rs1541516 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
LRRC37A4P	No	Adipose Subcutaneous	cis	GTEx