PTSDgene database

SNP Report

Basic Info
Name rs1541516 dbSNP Ensembl
Location 7:31082927 - 31082927(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.271166
Annotation downstream_gene_variant; upstream_gene_variant; intron_variant
Variant Effect downstream_gene_variant(ENST00000431811); upstream_gene_variant(ENST00000436116); intron_variant(ENST00000409363, ENST00000304166, ENST00000409489, ENST00000396211, ENST00000614107)
SIFT Annotation deleterious; tolerated
SIFT Variant Effect deleterious(ENST00000409489, ENST00000614107, ENST00000396211); tolerated(ENST00000304166, ENST00000409363)
PolyPhen Annotation possibly_damaging; probably_damaging
PolyPhen Variant Effect possibly_damaging(ENST00000614107, ENST00000396211); probably_damaging(ENST00000409489, ENST00000304166, ENST00000409363)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region;Chromatin interactive region
Chromatin State Weak transcription;Enhancers;Strong transcription;Bivalent Enhancer;Genic enhancers;Bivalent/Poised TSS
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ressler, K. J.,2011 PTSD diagnosis Females: P-value=0.858, males: P-value=0.941 Females: P-value=0.858, males: P-value=0.941 No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs1541516 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx