PTSDgene database

SNP Report

Basic Info
Name rs1500899 dbSNP Ensembl
Location 8:95522762 - 95522762(+)
Variant Seq T
Ancestral Allele T
Ref Seq G
Minor Allele Frequence 0.297125
Annotation intron_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000517437, ENST00000519366, ENST00000521905); non_coding_transcript_variant(ENST00000517437, ENST00000519366, ENST00000521905)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000286688)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000286688)
rSNP? No Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Inactive region
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Xie, P.,2013 Lifetime PTSD Trauma Exposed African Americans: in GWAS,P-value=9.94E-06,i...... Trauma Exposed African Americans: in GWAS,P-value=9.94E-06,in replication,P-value=NT,in combined, P-value=NT. More... No significant signals were observed in the African American...... No significant signals were observed in the African American part of the sample. Genome-wide association study analyses restricted to trauma-exposed individuals yielded very similar results. More... Trend

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
C8orf37 chromosome 8 open reading frame 37 8q22.1 1(0/0/1)
C8orf37-AS1 C8orf37 antisense RNA 1 8q22.1 Mapped by Literature SNP

SNPs in LD with rs1500899 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-259G18.3 No Adipose Subcutaneous cis GTEx