SNP Report

Basic Info

Name	rs10502692 dbSNP Ensembl
Location	18:38460388 - 38460388(+)
Variant Seq	T
Ancestral Allele	C
Ref Seq	C
Minor Allele Frequence	0.21905
Annotation	downstream_gene_variant
SIFT Annotation	deleterious_-_low_confidence; tolerated_-_low_confidence
SIFT Variant Effect	deleterious_-_low_confidence(ENST00000601392); tolerated_-_low_confidence(ENST00000420428, ENST00000601019, ENST00000591282, ENST00000588597, ENST00000361795, ENST00000591287, ENST00000334919, ENST00000603232)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000420428, ENST00000601019, ENST00000591282, ENST00000588597, ENST00000361795, ENST00000601392, ENST00000591287, ENST00000334919, ENST00000603232)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Enhancers
No. of Marker's Association Results	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Guffanti, G.,2013	PTSD	In the DNHS subjects: B=-4.53, P-value=4.46E-06, OR=0.35, 9...... In the DNHS subjects: B=-4.53, P-value=4.46E-06, OR=0.35, 95%CI=0.22-0.55. More...		Trend

SNP related genes (count: 0)

SNPs in LD with rs10502692 (count: 10)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs17639821	rs10502692	downstream_gene_variant	0.9146[EUR]; 0.8857[AMR]
rs12373278	rs10502692	downstream_gene_variant	1.0000[EUR]; 0.9343[AMR]
rs10502694	rs10502692	downstream_gene_variant	0.9763[EUR]; 0.9343[AMR]
rs1196400	rs10502692	downstream_gene_variant	0.9607[EUR]; 0.9021[AMR]
rs9962925	rs10502692	downstream_gene_variant	0.9688[EUR]; 0.8909[AMR]
rs55921657	rs10502692	downstream_gene_variant	0.9767[EUR]; 0.9179[AMR]
rs11082081	rs10502692	downstream_gene_variant	1.0000[EUR]; 0.9343[AMR]
rs9954810	rs10502692	downstream_gene_variant	0.9921[EUR]; 0.9053[AMR]
rs17559315	rs10502692	downstream_gene_variant	0.9298[EUR]; 0.8857[AMR]
rs9965620	rs10502692	downstream_gene_variant	0.9764[EUR]; 0.9053[AMR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
RP11-707O23.5	No	Adipose Subcutaneous	cis	GTEx