PTSDgene database

SNP Report

Basic Info
Name rs10268647 dbSNP Ensembl
Location 7:31075262 - 31075262(+)
Variant Seq G
Ancestral Allele A
Ref Seq A
Minor Allele Frequence 0.0716853
Annotation intron_variant
Variant Effect intron_variant(ENST00000409489, ENST00000396211, ENST00000431811, ENST00000614107, ENST00000409363, ENST00000304166)
SIFT Annotation tolerated_-_low_confidence; tolerated
SIFT Variant Effect tolerated_-_low_confidence(ENST00000409489, ENST00000304166, ENST00000614107, ENST00000396211, ENST00000409363); tolerated(ENST00000431811)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000409489, ENST00000304166, ENST00000614107, ENST00000431811, ENST00000396211, ENST00000409363)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Strong transcription;Enhancers;Genic enhancers;Bivalent Enhancer
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ressler, K. J.,2011 PTSD diagnosis Females: P-value=0.794, males: P-value=0.935 Females: P-value=0.794, males: P-value=0.935 No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs10268647 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx