PTSDgene database

SNP Report

Basic Info
Name rs10081254 dbSNP Ensembl
Location 7:31082056 - 31082056(+)
Variant Seq T
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.137979
Annotation downstream_gene_variant; upstream_gene_variant; intron_variant
Variant Effect downstream_gene_variant(ENST00000431811); upstream_gene_variant(ENST00000436116); intron_variant(ENST00000409363, ENST00000396211, ENST00000614107, ENST00000304166, ENST00000409489)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000304166, ENST00000396211, ENST00000614107, ENST00000409489, ENST00000409363)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000304166, ENST00000396211, ENST00000614107, ENST00000409489, ENST00000409363)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription;Enhancers;Bivalent Enhancer;Strong transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ressler, K. J.,2011 PTSD diagnosis Females: P-value=0.239, males: P-value=0.845 Females: P-value=0.239, males: P-value=0.845 No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs10081254 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx