PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs10081254 dbSNP Ensembl
Location	7:31082056 - 31082056(+)
Variant Seq	T
Ancestral Allele	C
Ref Seq	C
Minor Allele Frequence	0.137979
Annotation	downstream_gene_variant; upstream_gene_variant; intron_variant
Variant Effect	downstream_gene_variant(ENST00000431811); upstream_gene_variant(ENST00000436116); intron_variant(ENST00000409363, ENST00000396211, ENST00000614107, ENST00000304166, ENST00000409489)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000304166, ENST00000396211, ENST00000614107, ENST00000409489, ENST00000409363)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000304166, ENST00000396211, ENST00000614107, ENST00000409489, ENST00000409363)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	Chromatin interactive region
Chromatin State	Weak transcription;Enhancers;Bivalent Enhancer;Strong transcription
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Ressler, K. J.,2011	PTSD diagnosis	Females: P-value=0.239, males: P-value=0.845 Females: P-value=0.239, males: P-value=0.845	No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	7p14.3	19(8/11/0)

SNPs in LD with rs10081254 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
LRRC37A4P	No	Adipose Subcutaneous	cis	GTEx