Gene Report

Basic Info

Approved Symbol	USP22
Previous Symbol	USP3L
Symbol Alias	KIAA1063
Approved Name	ubiquitin specific peptidase 22
Previous Name	"ubiquitin specific protease 22\|ubiquitin specific peptidase 3-like"
Location	17p11.2
Position	chr17:20999593-21043760, -1
External Links	HGNC: 12621 Entrez Gene: 23326 Ensembl: ENSG00000124422 UCSC: uc002gym.4
No. of Association Results	0. Gene is from "rSNP target"
Annotation Type	rSNP target

Gene functional annotation

Gene related GO terms (count: 21)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0008234	cysteine-type peptidase activity	molecular function	IEA	4
GO:0010485	H4 histone acetyltransferase activity	molecular function	IDA[18206973]	1
GO:0006511	ubiquitin-dependent protein catabolic process	biological process	IEA	5
GO:0043967	histone H4 acetylation	biological process	IDA[18206973]	1
GO:0000124	SAGA complex	cellular component	IDA[18206972\|18206973]	1
GO:0070461	SAGA-type complex	cellular component	IDA[18838386]	1
GO:0004843	thiol-dependent ubiquitin-specific protease activity	molecular function	IDA[16378762]; IMP[18206973]	3
GO:0006325	chromatin organization	biological process	TAS	6
GO:0016574	histone ubiquitination	biological process	IDA[18469533]	2
GO:0007049	cell cycle	biological process	IEA	7
GO:0006351	transcription, DNA-templated	biological process	IEA	21
GO:0003713	transcription coactivator activity	molecular function	IDA[18206972]	4
GO:0016579	protein deubiquitination	biological process	IDA[16378762]	3
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	molecular function	IMP[18206972]	1
GO:0005515	protein binding	molecular function	IPI[18206972\|19615732\|21779003\|24561192\|25416956]	169
GO:0008270	zinc ion binding	molecular function	IEA	26
GO:0009790	embryo development	biological process	NAS[16378762]	1
GO:0019899	enzyme binding	molecular function	IPI[23382074]	13
GO:0016578	histone deubiquitination	biological process	IDA[18206972\|18206973]	1
GO:0045893	positive regulation of transcription, DNA-templated	biological process	IMP[18206973]	11
GO:0045931	positive regulation of mitotic cell cycle	biological process	IMP[18206973]	3

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 5)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
USP22	USP27X	No	--	--	19615732 , 19615732
USP22	TAF6L	No	--	--	19615732 , 19615732
USP22	TRRAP	No	--	--	19615732 , 18206972 , 19615732
USP22	POFUT2	No	--	--	19615732 , 19615732
USP22	CNOT1	No	--	--	19615732 , 19615732