Gene Report

Basic Info

Approved Symbol	TRPA1
Previous Symbol	ANKTM1
Approved Name	transient receptor potential cation channel, subfamily A, member 1
Previous Name	ankyrin-like with transmembrane domains 1
Location	8q13
Position	chr8:72019917-72075617, -1
External Links	HGNC: 497 Entrez Gene: 8989 Ensembl: ENSG00000104321 UCSC: uc003xza.3
No. of Association Results	0. Gene is from "rSNP target"
Annotation Type	rSNP target

Gene functional annotation

Gene related GO terms (count: 24)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0048265	response to pain	biological process	IEA	4
GO:0014070	response to organic cyclic compound	biological process	IEA	3
GO:0019233	sensory perception of pain	biological process	IMP[20547126]	9
GO:0050955	thermoception	biological process	IEA	1
GO:0034220	ion transmembrane transport	biological process	TAS	9
GO:0042493	response to drug	biological process	IEA	25
GO:0010033	response to organic substance	biological process	IMP[20547126]	2
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	biological process	IEA	3
GO:0032421	stereocilium bundle	cellular component	IEA	1
GO:0097604	temperature-gated cation channel activity	molecular function	IDA[20547126]	1
GO:0055085	transmembrane transport	biological process	TAS	14
GO:0005887	integral component of plasma membrane	cellular component	IMP[20547126\|25855297]	36
GO:0015267	channel activity	molecular function	TAS[10066796]	2
GO:0050968	detection of chemical stimulus involved in sensory perception of pain	biological process	IEA	1
GO:0035556	intracellular signal transduction	biological process	IDA[20547126]; IMP[25855297]	10
GO:0007166	cell surface receptor signaling pathway	biological process	IEA	16
GO:0006811	ion transport	biological process	TAS[10066796]	10
GO:0005886	plasma membrane	cellular component	TAS	99
GO:0009409	response to cold	biological process	IEA	3
GO:0005622	intracellular	cellular component	IDA[20547126]; IMP[25855297]	15
GO:0070588	calcium ion transmembrane transport	biological process	IMP[20547126\|25855297]; TAS	5
GO:0042542	response to hydrogen peroxide	biological process	IEA	3
GO:0051209	release of sequestered calcium ion into cytosol	biological process	IDA[20547126]; IMP[25855297]	3
GO:0051289	protein homotetramerization	biological process	IDA[25855297]	4

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 2)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
TRPA1	UBC	No	--	--	16500080
TRPA1	CYLD	No	--	--	16500080