Gene Report

Basic Info

Approved Symbol	PARD6B
Symbol Alias	PAR-6B
Approved Name	par-6 family cell polarity regulator beta
Previous Name	"par-6 (partitioning defective 6, C.elegans) homolog beta\|par-6 partitioning defective 6 homolog beta (C. elegans)"
Location	20q13.13
Position	chr20:50731544-50756795, 1
External Links	HGNC: 16245 Entrez Gene: 84612 Ensembl: ENSG00000124171 UCSC: uc002xvo.3
No. of Association Results	0. Gene is from "rSNP target"
Annotation Type	rSNP target

Gene functional annotation

Gene related GO terms (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0034329	cell junction assembly	biological process	TAS	4
GO:0005829	cytosol	cellular component	TAS	78
GO:0005886	plasma membrane	cellular component	IDA[12545177]; TAS	99
GO:0005515	protein binding	molecular function	IPI[11260256\|12725730\|14676191\|15254234\|20936779\|25416956\|25852190\|26496610]	169
GO:0007043	cell-cell junction assembly	biological process	TAS[12545177]	1
GO:0007163	establishment or maintenance of cell polarity	biological process	TAS[14676191]	2
GO:0070062	extracellular exosome	cellular component	IDA[19056867]	58
GO:0005634	nucleus	cellular component	IEA	81
GO:0030334	regulation of cell migration	biological process	TAS[14676191]	2
GO:0007049	cell cycle	biological process	IEA	7
GO:0070830	bicellular tight junction assembly	biological process	TAS	1
GO:0043234	protein complex	cellular component	IEA	10
GO:0006461	protein complex assembly	biological process	IDA[12545177]	6
GO:0045177	apical part of cell	cellular component	IEA	3
GO:0005923	bicellular tight junction	cellular component	IDA[12545177]	5
GO:0045216	cell-cell junction organization	biological process	TAS	1
GO:0007409	axonogenesis	biological process	TAS[14676191]	6
GO:0051301	cell division	biological process	IEA	5
GO:0005737	cytoplasm	cellular component	IDA	109
GO:0005938	cell cortex	cellular component	IEA	4

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in PTSDgene
hsa04530	Tight junction	3

Gene related interactors from protein-protein interactions data in PINA v2 (count: 2)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
PARD6B	PARD6A	No	--	association	14676191 , 14676191 , 14676191 , 14676191 , 14676191
PARD6B	DMBT1	No	--	association	14676191 , 14676191