PTSDgene database

SNP Report

Basic Info
Name rs9725031 dbSNP Ensembl
Location 1:232308709 - 232308709(+)
Variant Seq T
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.122005
Annotation downstream_gene_variant; upstream_gene_variant
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000439617, ENST00000366637, ENST00000620189)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000439617, ENST00000366637, ENST00000620189)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Wolf, E. J.,2014 Dissociative symptom severity Linear regression: B=1.13, SE=0.25, P-value=7.72E-06, R Linear regression: B=1.13, SE=0.25, P-value=7.72E-06, R2=0.04. Sex and SNP effects were found for rs9725031: B(interaction) =-1.48, P-value= .004; B(men)=0.57, P-value=.07; B(women)=2.05, P-value=1.17E-06. More... It showed suggestive evidence of association with dissociati...... It showed suggestive evidence of association with dissociation. In follow-up analyses, the association between this SNP and dissociation severity remained significant after covarying for PTSD severity. And it showed suggestive evidence of an association with sex, such that the effects were greater in women compared to men. More... Trend

SNP related genes (count: 0)

SNPs in LD with rs9725031 (count: 5)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-259G18.3 No Adipose Subcutaneous cis GTEx