SNP Report
Basic Info
| Name | rs8036584 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 15:32114089 - 32114089(+) | ||
| Variant Seq | C | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.134585 | ||
| Annotation | intron_variant; NMD_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000437966, ENST00000454250, ENST00000306901); NMD_transcript_variant(ENST00000437966) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000306901, ENST00000454250) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000306901, ENST00000454250) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Kimbrel, N. A.,2015 | PTSD | In the NHW sample, main effect: P-value=0.005739. In the NHW sample, main effect: P-value=0.005739. | Nominally significant associations (p<.05) were observed, bu...... Nominally significant associations (p<.05) were observed, but it didn't met multiple-testing threshold. More... | Significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Kimbrel, N. A.,2015 | PTSD | Smoking status | GxE interactions among NHW participants: P-value=0.5851. GxE interactions among NHW participants: P-value=0.5851. | No GxE interactions were statistically significant among NHW...... No GxE interactions were statistically significant among NHW participants. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| CHRNA7 | cholinergic receptor, nicotinic alpha 7 | 15q13.3 | 1(1/0/0) |
SNPs in LD with rs8036584 (count: 11)
Literature-origin SNPs (count: 0)
LD-proxies (count: 11)
SNP related eQTL (count: 1)