SNP Report
Basic Info
| Name | rs28358884 dbSNP Ensembl | ||
|---|---|---|---|
| Location | MT:8414 - 8414(+) | ||
| Variant Seq | T | ||
| Ancestral Allele | C | ||
| Ref Seq | C | ||
| Annotation | downstream_gene_variant; missense_variant; upstream_gene_variant | ||
| Variant Effect | downstream_gene_variant(ENST00000387382, ENST00000387377, ENST00000361739, ENST00000361390, ENST00000361453, ENST00000387421, ENST00000387365, ENST00000361624, ENST00000387419); missense_variant(ENST00000361851); upstream_gene_variant(ENST00000361567, ENST00000361227, ENST00000361381, ENST00000387405, ENST00000387449, ENST00000387429, ENST00000387400, ENST00000387372, ENST00000387416, ENST00000361335, ENST00000387409, ENST00000387392, ENST00000387441, ENST00000362079, ENST00000387456, ENST00000361899, ENST00000387439) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000361851) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000361851) | ||
| rSNP? | No Link in rVarBase | ||
| Related Regulatory Elements | N.A. | ||
| Chromatin State | N.A. | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 0; Trend: 1) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Flaquer, A.,2015 | PTSD status | B= ?0.954, P-value=1.9E-05, adjusted P-value=0.037 B= ?0.954, P-value=1.9E-05, adjusted P-value=0.037 | This SNP was found to be associated with full PTSD. This SNP was found to be associated with full PTSD. | Trend |
SNP related genes (count: 27)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| MT-ATP6 | mitochondrially encoded ATP synthase 6 | mitochondria | Mapped by Literature SNP |
| MT-TI | mitochondrially encoded tRNA isoleucine | mitochondria | Mapped by Literature SNP |
| MT-CO1 | mitochondrially encoded cytochrome c oxidase I | mitochondria | Mapped by Literature SNP |
| MT-TW | mitochondrially encoded tRNA tryptophan | mitochondria | Mapped by Literature SNP |
| MT-ATP8 | mitochondrially encoded ATP synthase 8 | mitochondria | 1(0/0/1) |
| MT-TS1 | mitochondrially encoded tRNA serine 1 (UCN) | mitochondria | Mapped by Literature SNP |
| MT-TK | mitochondrially encoded tRNA lysine | mitochondria | Mapped by Literature SNP |
| MT-ND2 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 | mitochondria | Mapped by Literature SNP |
| MT-TH | mitochondrially encoded tRNA histidine | mitochondria | Mapped by Literature SNP |
| MT-TM | mitochondrially encoded tRNA methionine | mitochondria | Mapped by Literature SNP |
| MT-ND1 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | mitochondria | Mapped by Literature SNP |
| MT-ND4 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | mitochondria | Mapped by Literature SNP |
| MT-TA | mitochondrially encoded tRNA alanine | mitochondria | Mapped by Literature SNP |
| MT-TR | mitochondrially encoded tRNA arginine | mitochondria | Mapped by Literature SNP |
| MT-ND3 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 | mitochondria | Mapped by Literature SNP |
| MT-TC | mitochondrially encoded tRNA cysteine | mitochondria | Mapped by Literature SNP |
| MT-TS2 | mitochondrially encoded tRNA serine 2 (AGU/C) | mitochondria | Mapped by Literature SNP |
| MT-CO3 | mitochondrially encoded cytochrome c oxidase III | mitochondria | Mapped by Literature SNP |
| MT-ND4L | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L | mitochondria | Mapped by Literature SNP |
| MT-CO2 | mitochondrially encoded cytochrome c oxidase II | mitochondria | Mapped by Literature SNP |
| MT-TY | mitochondrially encoded tRNA tyrosine | mitochondria | Mapped by Literature SNP |
| MT-ND5 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | mitochondria | 1(0/0/1) |
| MT-TG | mitochondrially encoded tRNA glycine | mitochondria | Mapped by Literature SNP |
| MT-TN | mitochondrially encoded tRNA asparagine | mitochondria | Mapped by Literature SNP |
| MT-TD | mitochondrially encoded tRNA aspartic acid | mitochondria | Mapped by Literature SNP |
| MT-TL2 | mitochondrially encoded tRNA leucine 2 (CUN) | mitochondria | Mapped by Literature SNP |
| MT-TQ | mitochondrially encoded tRNA glutamine | mitochondria | Mapped by Literature SNP |
SNPs in LD with rs28358884 (count: 0)
SNP related eQTL (count: 1)