PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs211130 dbSNP Ensembl
Location	11:17995326 - 17995326(+)
Variant Seq	T
Ancestral Allele	C
Ref Seq	C
Minor Allele Frequence	0.458866
Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect	downstream_gene_variant(ENST00000532212); intron_variant(ENST00000533328, ENST00000527494, ENST00000529440, ENST00000528200, ENST00000532265, ENST00000530613, ENST00000530925, ENST00000532546, ENST00000525422, ENST00000532389, ENST00000265965, ENST00000525920, ENST00000529728, ENST00000529151); NMD_transcript_variant(ENST00000533328, ENST00000527494, ENST00000530925, ENST00000532546, ENST00000525422); non_coding_transcript_variant(ENST00000529440)
SIFT Annotation	tolerated_-_low_confidence; tolerated
SIFT Variant Effect	tolerated_-_low_confidence(ENST00000530925); tolerated(ENST00000530613, ENST00000525422, ENST00000527494, ENST00000265965, ENST00000529728, ENST00000532265, ENST00000532389, ENST00000528200)
PolyPhen Annotation	benign; possibly_damaging
PolyPhen Variant Effect	benign(ENST00000530613, ENST00000525422, ENST00000527494, ENST00000265965, ENST00000529728, ENST00000532265, ENST00000532389, ENST00000528200); possibly_damaging(ENST00000530925)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription;Enhancers;Strong transcription;Genic enhancers
No. of Marker's Association Results	0 (Positive: 0; Negative: 0; Trend: 0)
Source	LD-proxy

SNP related association results

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
SERGEF	secretion regulating guanine nucleotide exchange factor	11p14.3	Mapped by LD-proxy, rSNP target

SNPs in LD with rs211130 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
LRRC37A4P	No	Adipose Subcutaneous	cis	GTEx