PTSDgene database

Variant Report

Basic Info
Name 5-HTTVNTR
Type VNTR
Location promoter
Related Gene SLC6A4
No. of Association Result 1 (Positive: 1; Negative: 0; Trend: 0)

Variant related studies

Normal genetic study related association result (count: 1)

Reference Phenotype Statistical Values Author Comments Marker's Category
Tian, Y.,2015 PTSD Allele frequence (10 vs 12): P-value=0.002. Genotype freque...... Allele frequence (10 vs 12): P-value=0.002. Genotype frequence (10/10 vs 10/12 vs 12/12): P-value<0.001. More... We found significant differences in the 5-HTTVNTR genotype b...... We found significant differences in the 5-HTTVNTR genotype between adolescents with and without PTSD, and the frequency of the 10 allele was significantly higher in those with PTSD compared with controls. More... Significant

Gene*Environment study related association results (count: 1)

Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Tian, Y.,2015 PTSD Earthquake exposure Interaction effect of genotype and earthquake exposure: OR=4...... Interaction effect of genotype and earthquake exposure: OR=4.612, 95%CI=1.215-17.505, P-value=0.025. More... The interaction effects of this genotype with earthquake exp...... The interaction effects of this genotype with earthquake exposure was statistically significant. More... Significant