PTSDgene database

Study Report

Study Information
Basic Info
Reference
Citation Donaldson, Z. R., et al. (2016). "The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription." Transl Psychiatry 6: e746.
Phenotype PTSD diagnosis
Trauma Various
Study Design Cross-sectional study
Study Type Candidate gene association study, Gene-environment interaction study
Sample Size 1233 samples
SNP/Marker Size 1 SNP
Predominant Ethnicity Black
Population American
Gender 480 males, 753 females
Age Mean age=40.11 years,SD=13.4.

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs6295 PTSD diagnosis HTR1A OR=1.282, P-value=0.128. Control for childhood trauma: OR=1.265, P-value=0.175. Control for non-childhood trauma: OR=1.328, P-value=0.095. We did not observe a significant association between rs6295 ...... We did not observe a significant association between rs6295 and current PTSD. More... Non-significant

Gene * Environment result reported by this study (count: 2)
Marker Phenotype Related Gene Environment Statistical Values Author Comments Marker's Category
rs6295 PTSD diagnosis HTR1A Childhood trauma P-value>0.05 No significant associations were observed. No significant associations were observed. Non-significant
rs6295 PTSD diagnosis HTR1A Non-childhood trauma P-value>0.05 No significant associations were observed. No significant associations were observed. Non-significant