PTSDgene database

SNP Report

Basic Info
Name rs3093066 dbSNP Ensembl
Location 1:159713309 - 159713309(+)
Variant Seq T
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.0770767
Annotation 3_prime_UTR_variant; intron_variant; non_coding_transcript_variant
Variant Effect 3_prime_UTR_variant(ENST00000255030); intron_variant(ENST00000368110, ENST00000368112, ENST00000489317, ENST00000368111, ENST00000437342, ENST00000473196); non_coding_transcript_variant(ENST00000489317, ENST00000473196)
SIFT Annotation deleterious; tolerated
SIFT Variant Effect deleterious(ENST00000368112, ENST00000368110, ENST00000368111); tolerated(ENST00000437342, ENST00000255030)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000368112, ENST00000368110, ENST00000368111); possibly_damaging(ENST00000437342, ENST00000255030)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Active TSS;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Michopoulos, V.,2015 PTSD symptoms T=0.66, P-value=0.51 T=0.66, P-value=0.51 No significant effect on PTSD symptoms. No significant effect on PTSD symptoms. Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CRP C-reactive protein, pentraxin-related 1q23.2 3(2/1/0)

SNPs in LD with rs3093066 (count: 10)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx