PTSDgene database

SNP Report

Basic Info
Name rs2073837 dbSNP Ensembl
Location 9:133657806 - 133657806(+)
Variant Seq A
Ancestral Allele A
Ref Seq G
Minor Allele Frequence 0.342851
Annotation upstream_gene_variant; intron_variant
Variant Effect upstream_gene_variant(ENST00000425189); intron_variant(ENST00000393056)
SIFT Annotation tolerated_-_low_confidence
SIFT Variant Effect tolerated_-_low_confidence(ENST00000371868)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000371868)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region;CpG island;lncRNA
Chromatin State Weak transcription;Bivalent Enhancer;Enhancers;Flanking Active TSS
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD diagnosis P-value=0.071 P-value=0.071 Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... Non-significant


SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DBH-AS1 DBH antisense RNA 1 9q34.2 Mapped by Literature SNP, Mapped by LD-proxy
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 4(0/4/0)

SNPs in LD with rs2073837 (count: 11)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 11)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx