PTSDgene database

SNP Report

Basic Info
Name rs12670991 dbSNP Ensembl
Location 7:31049832 - 31049832(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.134784
Annotation upstream_gene_variant
Variant Effect upstream_gene_variant(ENST00000409363, ENST00000304166, ENST00000614107)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000326139, ENST00000409904)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000326139, ENST00000409904)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region
Chromatin State Weak transcription;Bivalent Enhancer;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ressler, K. J.,2011 PTSD diagnosis Females: P-value=0.603, males: P-value=0.71 Females: P-value=0.603, males: P-value=0.71 No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs12670991 (count: 1)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx