PTSDgene database

SNP Report

Basic Info
Name rs11071588 dbSNP Ensembl
Location 15:61141379 - 61141379(+)
Variant Seq G
Ancestral Allele T
Ref Seq T
Minor Allele Frequence 0.448882
Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000557822, ENST00000560300, ENST00000559145, ENST00000551975, ENST00000335670, ENST00000561093); NMD_transcript_variant(ENST00000551975); non_coding_transcript_variant(ENST00000557822, ENST00000560300, ENST00000559145, ENST00000561093)
SIFT Annotation deleterious_-_low_confidence; tolerated
SIFT Variant Effect deleterious_-_low_confidence(ENST00000551975); tolerated(ENST00000335670)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000335670); possibly_damaging(ENST00000551975)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Logue, M. W.,2013 PTSD In the VA-African-American sample: OR=3.81, Nominal P-value...... In the VA-African-American sample: OR=3.81, Nominal P-value=6.77E-05, Adjusted P-value=0.018. In the Detroit sample: P-value=0.43. More... It was found to be nominally significantly associated with P...... It was found to be nominally significantly associated with PTSD in the VA-African-American sample. It remained significant after multiple-testing correction. But it was not significatnt in the Detroit sample. More... Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
RORA RAR related orphan receptor A 15q21-q22 6(4/2/0)

SNPs in LD with rs11071588 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-259G18.3 No Adipose Subcutaneous cis GTEx